Monthly Archives: September 2011

New Medical Device Product Launch: Glen Mills / Zellwerk Z®RP Reactor System, Cell Tissue Engineering Apparatus Improves Laboratory Productivity

Commercial shipments have started of the “Glen Mills / Zellwerk Z®RP Reactor System” – a cell disruptor and high-pressure homogenizer that dramatically improves cell culture and tissue engineering capabilities for laboratories.  “Based on a 60 year old medical device, that is still valid, the System was newly engineered by Sigma Design Company of Springfield, New Jersey with great operational and safety improvements”, explained Mr. Stanley Goldberg, President of Glen Mills, Inc., Clifton, NJ.  Sigma Design completed the new product design and engineering of the pilot System in December 2010 and went to full commercial production by August 2011.

GlennMills Reactor System – Designed & Assembled by Sigma Design Co

The System with Glen Mills/Zellwerk Z®RP Technology,utilizes high pressure to burst cell walls. The GM French Press uses a hydraulic press and carefully machined parts to produce pressures up to 40,000 psi. Culturing of adherent cells/tissues in a sterile natural 3-D environment continuously for over 12 months allows for impressive cell densities exceeding 10^10 all in a compact laboratory tabletop apparatus. This massive concentration of cells (up to 10,000x more than conventional systems), in the Glen Mills / Zellwerk Z®RP Reactor System opens new areas for development in medicine, cell research, tissue growth for replacements, large-scale biomedical production by perfusion, and others. The medical device equipment complies with GLP, GCP, GTP and GMP standards.

The Reactor System is currently being manufactured by Sigma Design Company at its Springfield, NJ location. However, in house production will shift over to Sigma’s new Middlesex, NJ expanded operations by the end of this year. Glen Mills  will continue to handle medical device sales to their end customers.

Made in USA · Made in New Jersey · Made by Sigma Design Company, LLC

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People Power: Introducing Nicholas Faust, Sigma’s Newest Team Member

A successful entrepreneur and a Stevens Institute of Technology grad, our newest member, Nicholas Faust, who began as an intern in January 2011, was hired full time in May 2011 and has settled nicely into the Sigma team.

Nicholas Faust of Sigma Design Company

Nick’s success with helping to launch a successful skateboard start-up company that relies on human energy dovetails nicely with one of his first assignments at Sigma – a renewable energy project to prototype a vehicle energy harvesting device.

Nick is excited by such green technology/renewable energy projects and also aspires to be involved with industrial automation technologies.  Nick earned both a Masters of Engineering in Product- Architecture and Engineering (May 2011) and Bachelor’s of Engineering in Mechanical Engineering (2009) from Stevens Institute of Technology in Hoboken, New Jersey.

When asked what he most enjoys about Sigma, Nick shared: “I think the breadth of projects at Sigma Design Company – from consumer products to medical devices to renewable energy projects, keeps it interesting and challenging. I’ve learned a great deal about the challenges of manufacturability. It has been a great transition from the academic to the professional world.”

Welcome aboard Nick!

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Welcome to the blog of Sigma Design Company, LLC. We are professional engineers, designers and manufacturing specialists located in central New Jersey. Join the conversation spur on technology commercialization and enable a new product manufacturing era in the USA!