Commercial shipments have started of the “Glen Mills / Zellwerk Z®RP Reactor System” – a cell disruptor and high-pressure homogenizer that dramatically improves cell culture and tissue engineering capabilities for laboratories. “Based on a 60 year old medical device, that is still valid, the System was newly engineered by Sigma Design Company of Springfield, New Jersey with great operational and safety improvements”, explained Mr. Stanley Goldberg, President of Glen Mills, Inc., Clifton, NJ. Sigma Design completed the new product design and engineering of the pilot System in December 2010 and went to full commercial production by August 2011.
The System with Glen Mills/Zellwerk Z®RP Technology,utilizes high pressure to burst cell walls. The GM French Press uses a hydraulic press and carefully machined parts to produce pressures up to 40,000 psi. Culturing of adherent cells/tissues in a sterile natural 3-D environment continuously for over 12 months allows for impressive cell densities exceeding 10^10 all in a compact laboratory tabletop apparatus. This massive concentration of cells (up to 10,000x more than conventional systems), in the Glen Mills / Zellwerk Z®RP Reactor System opens new areas for development in medicine, cell research, tissue growth for replacements, large-scale biomedical production by perfusion, and others. The medical device equipment complies with GLP, GCP, GTP and GMP standards.
The Reactor System is currently being manufactured by Sigma Design Company at its Springfield, NJ location. However, in house production will shift over to Sigma’s new Middlesex, NJ expanded operations by the end of this year. Glen Mills will continue to handle medical device sales to their end customers.
Made in USA · Made in New Jersey · Made by Sigma Design Company, LLC